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The absence of HIF-1 can result in intestinal wall damage, dysbiosis (e.g., increased Akkermansia abundance and decreased lactobacilli levels), heightened endotoxemia, and induced ALD

Notably, previous MRS studies in ASD, predominantly conducted using 1.53 T MR scanners, have not succeeded in quantifying the metabolite levels, resulting in inconsistent findings [21,22,23,24,25,26]

Patients with Parkinson's disease, those on dopamine agonist therapy for restless legs syndrome, or individuals treated with dopamine-blocking antipsychotics may experience unpredictable drug interactions

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Zhang X, Peng L, Dai Y, Sheng X, Chen S, Xie Q